Comparison of 68Ga-DOTA-FAPI and 18FDG PET/CT imaging modalities in the detection of liver metastases in patients with gastrointestinal system cancer

AbstractPurpose We aimed to compare the diagnostic performance of PET/CT imaging performed with 68Ga-DOTA-FAPI and 18FDG in detection liver metastases patients gastrointestinal system (GIS) cancer. Methods A total 31 who underwent 18F-FDG examinations diagnosed GIS cancer (15 colorectal, 9 pancreas, 4 stomach 3 other cancers) were included study. The presence metastasis was decided based on histopathologic diagnosis, PET/CT, radiologic or tumor biomarker findings, both findings compared patient lesion basis. Results Of patients, 28 found as true positive 68Ga-DOTA-FAPI-PET/CT 17 18FDG-PET/CT. 98 metastatic lesions determined according our criteria, 92 65 There a statistically significant difference between modalities comparisons (p < 0.05). When semiquantitative values (SUVmax, mlr) obtained from two methods, mlr showed all subgroups Conclusion It concluded that superior over 18FDG-PET/CT cancers it can be complementary method especially negative cases